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Man, I was so off in my guess!

Calories: Consuming more calories than the body needs leads to weight gain and eventually obesity. Obesity is a well-documented risk factor for heart disease, stroke, and type 2 diabetes. In addition, excessive caloric intake without corresponding physical activity can lead to metabolic syndrome, a cluster of conditions that increase the risk of cardiovascular diseases.
Saturated Fat: Saturated fat has a well-established role in raising LDL cholesterol, which contributes to plaque buildup in the arteries. According to the American Heart Association, diets high in saturated fats are directly linked to cardiovascular diseases, such as heart attacks and strokes. The Five Guys Cheeseburger contains nearly 73% more saturated fat than other comparable fast food burgers, making it especially dangerous for heart health.
Sodium: High sodium levels have been repeatedly linked to hypertension. Consuming a single burger with such a high sodium content increases the risk of developing high blood pressure, a key contributor to heart disease. Excessive sodium intake is also associated with increased risk of stroke and kidney disease.
Other Studies on Fast Food Burgers and Health Risks

In addition to PlushCare’s study, other research supports the link between fast food burgers and poor health outcomes. A comprehensive review by the National Institutes of Health (NIH) examined the broader effects of fast food consumption on public health. It found that frequent fast food consumption is associated with an increased risk of obesity, insulin resistance, and metabolic syndrome.

A similar study published in Circulation by the American Heart Association found that regular consumption of high-calorie fast food, particularly burgers and fries, significantly raises the risk of coronary heart disease. The study highlighted the impact of high saturated fat and sodium levels in these foods, particularly noting how they contribute to artery-clogging plaque and increased blood pressure.

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