Season Pork: Season the pork loin generously with salt and pepper.
Sear Pork: Heat olive oil in a large oven-safe skillet or Dutch oven over medium-high heat. Sear the pork loin on all sides until golden brown, about 3-4 minutes per side. Remove the pork from the skillet and set aside.
Make Sauce: In the same skillet, combine Coca-Cola, ketchup, soy sauce, brown sugar, garlic, Dijon mustard, Worcestershire sauce, ground ginger, and crushed red pepper flakes. Stir well to combine and bring to a simmer.
Cook Pork: Return the pork loin to the skillet, spooning some of the sauce over the top. Cover the skillet with a lid or foil.
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